An update on juvenile dermatomyositis.
Copyright policy )An update on juvenile dermatomyositis.
Juvenile dermatomyositis (JDM) is a rare, severe, autoimmune disease characterized by a small-vessel vasculopathy that primarily affects skin and muscle, but also lung, joints, gut and heart. Nowadays prompt recognition of this entity and aggressive treatment, when needed, improves outcomes and has decreased mortality that, before corticosteroid became a mainstay in therapy, could reach 40%.
- University of Parma Italy
- University of Chieti-Pescara Italy
Autoimmune diseases, Dermatomyositis; Autoimmune diseases; small-vessel vasculopathy, Dermatomyositis, 618, Antibodies, Monoclonal, Murine-Derived, Adrenal Cortex Hormones, Humans, Child, Autoantibodies, Skin, Antibodies, Monoclonal, Immunoglobulins, Intravenous, Infant, Dendritic Cells, Infliximab, Capillaries, Early Diagnosis, Child, Preschool, Disease Progression, Cytokines, small-vessel vasculopathy, Atrophy, Rituximab, Immunosuppressive Agents
Autoimmune diseases, Dermatomyositis; Autoimmune diseases; small-vessel vasculopathy, Dermatomyositis, 618, Antibodies, Monoclonal, Murine-Derived, Adrenal Cortex Hormones, Humans, Child, Autoantibodies, Skin, Antibodies, Monoclonal, Immunoglobulins, Intravenous, Infant, Dendritic Cells, Infliximab, Capillaries, Early Diagnosis, Child, Preschool, Disease Progression, Cytokines, small-vessel vasculopathy, Atrophy, Rituximab, Immunosuppressive Agents
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