
Functional heartburn is a frequent disease which should be considered when heartburn does not respond to proton pump inhibitor (PPI) treatment. Functional heartburn is defined in the Rome-III-criteria. Differential diagnoses like gastroesophageal reflux disease (GERD), non erosive reflux disease (NERD) and hypertensive esophagus are diagnosed employing an endoscopy and a 24h-pH-study. Since clinical trials are lacking, treatment approaches are empirical. Successful treatment includes adequate information of the patient, identification of the cardinal symptom and setting of realistic goals.
Gastrointestinal Diseases, Drug Resistance, Proton Pump Inhibitors, Gastric Acidity Determination, Antidepressive Agents, Diagnosis, Differential, Heartburn, Patient Education as Topic, Gastroscopy, Gastroesophageal Reflux, Dyspepsia
Gastrointestinal Diseases, Drug Resistance, Proton Pump Inhibitors, Gastric Acidity Determination, Antidepressive Agents, Diagnosis, Differential, Heartburn, Patient Education as Topic, Gastroscopy, Gastroesophageal Reflux, Dyspepsia
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