The article is devoted to the actual problem in modern medicine therapy of chronic apical periodontitis in the elderly age. It is shown that periodontitis remains till today the leading cause of tooth extraction in the elderly age; in addition, periodontitis can lead to serious complications such as periostitis, phlegmon, osteomyelitis, which creates additional scientific interest in the study of the above complications at the junction of the two specialties--gerontology and stomatology. In elderly patients regeneration after the periodontal infectious processes takes more time, in this case the traditional approach to treatment of inflammation in the periodontium shows frequent lack of regression of the focus of periapical destruction. Based on the results of the study it is proved that prolonged antiseptic and immune-stimulating effect of therapeutic paste PED used in conjunction with 5% liniment cycloferon, leads to a rapid and marked reduction in inflammatory activity in the affected area both at granulating, and at granulomatous forms of chronic periodontitis, and is accompanied by a significantly larger share of the achieved remission.