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Factores de riesgo cardiovascular entre pacientes con síndrome de Cushing, curados y no curados con respecto a un grupo control

Authors: Martínez Momblán, Ma. Antonia; Resmini, Eugenia; Barahona Constanzo, M. J.; Sucunza Alfonso, N.; Santos Vives, Alicia; Martí Ippoliti, C.; Roig García, O.; +2 Authors

Factores de riesgo cardiovascular entre pacientes con síndrome de Cushing, curados y no curados con respecto a un grupo control

Abstract

Objetivos: Describir los factores de riesgo cardiovascular que se presentan en el paciente con Síndrome de Cushing (SC), para establecer programas educativos adaptados a este grupo de pacientes. Método: El ámbito de estudio se desarrolló en el Hospital de Sant Pau, en el Servicio de Endocrinología. Se extrajeron datos de las Historias Clínicas de los pacientes que fueron visitados en consultas con diagnóstico de SC en el 2005, realizándose una recogida retrospectiva. No se excluyó ningún paciente, independientemente de los años de duración de la patología, de las opciones terapéuticas o del tratamiento farmacológico recibido, incluyendo todos los pacientes con SC. Elaboramos una hoja de recogida de datos demográficos, clínicos (peso, índice de masa corporal, tensión arterial, perímetro abdominal) y analíticos (lípidos, glicemia); para el tratamiento informático se utilizó el programa SPSS. Resultados: El perímetro abdominal fue mayor en pacientes no curados (100.8 ±13.9cm) que en controles (89±12.8cm) (p<0.05). Respecto al peso no se encontraron diferencias significativas entre controles (69,9±13,3Kg), curados (69,9±16,5Kg) y no curados (76,4±16,5Kg). El IMC tampoco reflejó diferencias en los tres grupos en estudio: control (26,5±5,2), curados (27,8±6,4) y no curados (29,3±3,8). El colesterol fue más alto en los pacientes curados (5.90±0.92mmol/L) que en controles (5.38±1.07mmol/L) (p<0.05), al igual que los triglicéridos (1.20±0.51mmol/L versus controles 1.05±0.56mmol/L; p<0.05). Ambos grupos de pacientes presentaron presión sistólica mayor que los controles (curados,128.3±16.7mmHg p<0.05; no curados,134.1±13mmHg, p<0.001). Los no curados (78.6±9.2mmHg) presentaron además presión diastólica mayor que los controles (72.3±8.6, p<0.05) Fig.3. No observamos diferencias en la glicemia basal entre los 3 grupos de pacientes. Conclusiones: Los pacientes con SC, curados de su hipercortisolismo y con enfermedad activa presentan mayor riesgo cardiovascular y metabólico, comparados con el grupo control. La enfermera educadora deberá contemplar e incluir en los programas de prevención secundaria a dichos pacientes, para promocionar hábitos saludables, prevenir y controlar sus factores de riesgo. Palabras Clave Síndrome Cushing, educación sanitaria, factores de riesgo cardiovascular.

Country
Spain
Keywords

Cardiovascular system, Educació sanitària, Cardiovascular diseases, Síndrome de Cushing, Health education, Malalties cardiovasculars, Cardiology, Cushing's syndrome, Cardiologia, Sistema cardiovascular

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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