Antimicrobial activity of extracts and fractions from aerial parts of selected plants (Garcinia achachairu, Macrosiphonia velame, Rubus niveus and Pilea microphylla) against some pathogenic microorganisms.
Copyright policy )Antimicrobial activity of extracts and fractions from aerial parts of selected plants (Garcinia achachairu, Macrosiphonia velame, Rubus niveus and Pilea microphylla) against some pathogenic microorganisms.
As part of the program of our research group to search for new and effective substances from the Brazilian biodiversity, the present work evaluates the antibacterial activity of four species from the Brazilian flora (Garcinia achachairu, Macrosiphonia velame, Rubus niveus and Pilea microphylla) against Bacillus subtilis, Staphylococcus aureus and S. saprophyticus (Gram-positive bacteria), Escherichia coli (Gram-negative bacterium) and Candida albicans (yeast). The extracts of R. niveus and M. velame showed promising antibacterial activity with MICs, ranging from 1000 to 125 microg/mL. Bio-guided fractionation of M. velame yielded four compounds, with the highest inhibition being observed for compound 3, with a MIC of 125 microg/mL against S. aureus. The combinations of fractions 2 and 4 showed beneficial effect against Gram-positive bacteria (additive effect), suggesting a possible synergistic effect.
Apocynaceae, Anti-Infective Agents, Plant Extracts, Microbial Sensitivity Tests, Garcinia, Rosaceae
Apocynaceae, Anti-Infective Agents, Plant Extracts, Microbial Sensitivity Tests, Garcinia, Rosaceae
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).2 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!