Cellular differentiation.
Substantial evidence now points to DNA methylation playing a primary role in locking genes in the "off' condition. Specific hypomethylation events may be necessary but not sufficient for gene expression. 5-azacytidine is a useful drug to perturb DNA methylation patterns and determine the effects of these perturbations on gene expression.
Mice, Inbred C3H, Cell Cycle, Cell Differentiation, DNA, Acetates, Methylation, Mice, Adipose Tissue, Gene Expression Regulation, Azacitidine, Animals, DNA (Cytosine-5-)-Methyltransferases, Cell Division, Cells, Cultured, Triglycerides, Acetic Acid
Mice, Inbred C3H, Cell Cycle, Cell Differentiation, DNA, Acetates, Methylation, Mice, Adipose Tissue, Gene Expression Regulation, Azacitidine, Animals, DNA (Cytosine-5-)-Methyltransferases, Cell Division, Cells, Cultured, Triglycerides, Acetic Acid
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