
pmid: 24042407
handle: 11383/2094748
Metaiodobenzylguanidine (MIBG) was developed initially as a tracer for oncological imaging; when labeled with 123 I or 131 I, it may detect APUDomas, such as pheochromocytomas and paragangliomas. In the last years, MIBG has found an important role also in neurology and cardiology, as cardiac innervation tracer. Actually, MIBG cardiac imaging is a universally accepted method to estimate cardiac sympathetic innervations. This review covers the role of MIBG cardiac imaging in Parkinson disease and parkinsonisms, from the pathophysiological premises for cardiac denervation to new emerging data.
Lewy Body Disease, Tomography, Emission-Computed, Single-Photon, Sympathetic Nervous System, Presynaptic Terminals, Heart, Parkinson Disease, Multiple System Atrophy, Diagnosis, Differential, Iodine Radioisotopes, 3-Iodobenzylguanidine, Sympathetic Fibers, Postganglionic, Parkinsonian Disorders, Heart Conduction System, Humans, Supranuclear Palsy, Progressive, Radiopharmaceuticals, Sympathectomy, Diagnosis, Differential; Heart; Heart Conduction System; Humans; Lewy Body Disease; Multiple System Atrophy; Parkinson Disease; Parkinsonian Disorders; Presynaptic Terminals; Supranuclear Palsy, Progressive; Sympathectomy; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System; Tomography, Emission-Computed, Single-Photon; 3-Iodobenzylguanidine; Iodine Radioisotopes; Radiopharmaceuticals
Lewy Body Disease, Tomography, Emission-Computed, Single-Photon, Sympathetic Nervous System, Presynaptic Terminals, Heart, Parkinson Disease, Multiple System Atrophy, Diagnosis, Differential, Iodine Radioisotopes, 3-Iodobenzylguanidine, Sympathetic Fibers, Postganglionic, Parkinsonian Disorders, Heart Conduction System, Humans, Supranuclear Palsy, Progressive, Radiopharmaceuticals, Sympathectomy, Diagnosis, Differential; Heart; Heart Conduction System; Humans; Lewy Body Disease; Multiple System Atrophy; Parkinson Disease; Parkinsonian Disorders; Presynaptic Terminals; Supranuclear Palsy, Progressive; Sympathectomy; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System; Tomography, Emission-Computed, Single-Photon; 3-Iodobenzylguanidine; Iodine Radioisotopes; Radiopharmaceuticals
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