[Diabetes and osteoporosis].
Copyright policy )[Diabetes and osteoporosis].
Diabetes alters bone mass and/or quality and increases fracture risk. However, in type 2 diabetes, bone mineral density (BMD) is usually not diminished, pertaining to increased weight and fat mass, which complicates the diagnosis of osteoporosis by DXA (T-score <-2.5). Similarly, estimates of fracture probability by FRAX may underestimate fracture risk in type 2 diabetes. Adequate glycemic control with insulin and/or oral antidiabetics decreases fracture risk, whereas thiazolidinediones increase it. Eventually, osteoporosis drugs such as bisphosphonates and SERMs seem to have similar efficacy in diabetic and non-diabetic patients.
Selective Estrogen Receptor Modulators, Absorptiometry, Photon, Bone Density Conservation Agents, Diabetes Mellitus, Type 2, Bone Density, Humans, Hypoglycemic Agents, Osteoporosis, Osteoporotic Fractures
Selective Estrogen Receptor Modulators, Absorptiometry, Photon, Bone Density Conservation Agents, Diabetes Mellitus, Type 2, Bone Density, Humans, Hypoglycemic Agents, Osteoporosis, Osteoporotic Fractures
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