[Detection of beta-lactamases in the Bacteroides fragilis group].
Copyright policy )[Detection of beta-lactamases in the Bacteroides fragilis group].
One hundred and thirty three strains of Bacteroides fragilis group isolated from clinical specimen were tested for beta-lactamase activity against five beta-lactam antibiotics, ampicillin, cefaloridin, cefuroxime, cefotaxime and cefoxitin. The Minimal Inhibitory Concentration of antibiotics was determined using the agar dilution method. Beta-lactamase production was detected by a microbiological method in 128 of the 133 (96%) strains. The detected beta-lactamases had a broad-spectrum activity, hydrolyzing both penicillins and cephalosporins (101 strains). Some strains had a wide activity against beta-lactam antibiotics, including cefoxitin (7 strains); among these strains, 3 were found hydrolyzing imipenem.
Bacteroides fragilis, Dose-Response Relationship, Drug, Drug Resistance, Microbial, Isoelectric Point, In Vitro Techniques, beta-Lactams, beta-Lactamases, Anti-Bacterial Agents
Bacteroides fragilis, Dose-Response Relationship, Drug, Drug Resistance, Microbial, Isoelectric Point, In Vitro Techniques, beta-Lactams, beta-Lactamases, Anti-Bacterial Agents
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