Chronic prostatitis are caused by infection in 5-10% of cases and other entities are called "chronic pelvic pain syndrome". The current classifications are based on the presence or absence of inflammation or infection in the prostatic secretions. The new concept of clinical phenotype "UPOINT" offers six domains (urinary, psychosocial, organ-specific, infectious, neurological, systemic and related to muscle tension) and can guide treatment according to the phenotype expressed by the patient. The therapeutic approach is based on the first use of antibiotics with or without alpha-blockers. Depending on clinical response, supportive treatment should be considered. The role of psychological support remains essential. Few studies of effectiveness of a level 1 of evidence are available and the chronic pelvic pain syndrome remains a controversial entity in the etiology whose treatments are empirical. The authors review current knowledge on the best treatment suited to the "chronic prostatitis".