[AQP4 regulation for cerebral edema].

Min, Li; Shaojun, Chen; Xuequn, Chen; Jizeng, Du

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浙江大学学报. 医学版arrow_drop_down

浙江大学学报. 医学版

Article . 2013

Data sources: Europe PubMed Central

[AQP4 regulation for cerebral edema].

descriptionPublicationkeyboard_double_arrow_right Article 28 Jun 2013Journal:Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, volume 42 (issn: 1008-9292,

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Authors: Min, Li; Shaojun, Chen; Xuequn, Chen; Jizeng, Du;

pmid: 23505118

[AQP4 regulation for cerebral edema].

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Abstract

Water balance is one of the basic regulation mechanisms of homeostasis. There are 13 subtypes of aquaporins in mammals (AQP0-AQP12). In neural system, the AQP4 is mainly distributed in astrocytes. Phosphorylation and expression regulation of AQP4 is involved in the formation of brain edema, particularly in the clearance of vasogenic edema and the formation of cytotoxic edema. This article reviews regulations and functions of AQP4 in vasogenic edema and cytotoxic edema.

Related Organizations

Zhejiang Ocean University
China (People's Republic of)

Keywords

Aquaporin 4, Animals, Brain, Homeostasis, Humans, Brain Edema, Water-Electrolyte Balance

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