[Diagnosis of pheochromocytoma by 131I-MIBG scintigraphy].

N, Miyanaga; K, Hattori; H, Shiraiwa; S, Hinotsu; R, Nemoto; K, Koiso; T, Takeda; N, Ishikawa

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Article . 1990

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[Diagnosis of pheochromocytoma by 131I-MIBG scintigraphy].

descriptionPublicationkeyboard_double_arrow_right Article 27 Jun 1990 Japanese Journal:Hinyokika kiyo. Acta urologica Japonica, volume 36 (issn: 0018-1994,

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Authors: N, Miyanaga; K, Hattori; H, Shiraiwa; S, Hinotsu; R, Nemoto; K, Koiso; T, Takeda; +1 Authors

pmid: 2343801

[Diagnosis of pheochromocytoma by 131I-MIBG scintigraphy].

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Abstract

Between February, 1984, and June, 1988, 131I-metaiodobenzylguanidine (131I-MIBG) scintigraphy was performed on 48 patients with suspected pheochromocytoma at our hospital. Whole body image and/or spot images were obtained 24, 48 and 72 hours after injection of 0.5 mCi of 131I-MIBG. In 10 of 12 patients with surgically proven pheochromocytoma, 131I-MIBG was accumulated in the primary and metastatic tumor. 131I-MIBG scintigraphy was negative in 2 patients. One case of renal cyst had the accumulation of 131I-MIBG but the disease could be confirmed. By 131I-MIBG scintigraphy sensitivity was 83% (10/12), and specificity was 97% (35/36). Heart intensity was much higher in patients with nonpheochromocytoma than those with pheochromocytoma. Thus 131I-MIBG scintigraphy proved to be safe, non-invasive and specific in the diagnosis of pheochromocytoma.

Related Organizations

University of Tsukuba
Japan

Keywords

Adult, Male, Iodobenzenes, Adrenal Gland Neoplasms, Pheochromocytoma, Middle Aged, Iodine Radioisotopes, 3-Iodobenzylguanidine, Humans, Female, Radionuclide Imaging, Aged

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