Urinary thromboxane B2 and 2,3-dinor-thromboxane B2 in the neonate born at full-term age.
Copyright policy Urinary thromboxane B2 and 2,3-dinor-thromboxane B2 in the neonate born at full-term age.
We have developed a method for measurement of urinary 2,3-dinor-TXB2, which is a reflection of the actual rate of TXA2 synthesis by platelets in vivo. This determination was based on purification by high-pressure liquid chromatography and on measurement by RIA. After validation of the assay, we established the range of urinary Tx metabolites in healthy infants born at full-term during their first week of life. The 2,3-dinor-TXB2 levels were higher than in adults and declined gradually during the first seven days of life.
- KU Leuven Belgium
Male, Osmolar Concentration, Infant, Newborn, Radioimmunoassay, Tritium, Thromboxane B2, Evaluation Studies as Topic, Reference Values, Humans, Female, Chromatography, High Pressure Liquid
Male, Osmolar Concentration, Infant, Newborn, Radioimmunoassay, Tritium, Thromboxane B2, Evaluation Studies as Topic, Reference Values, Humans, Female, Chromatography, High Pressure Liquid
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