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[Normocalcemic primary hyperparathyroidism: a growing problem].

Authors: Guillermo, Martínez Díaz-Guerra; Sonsoles, Guadalix Iglesias; Federico, Hawkins Carranza;

[Normocalcemic primary hyperparathyroidism: a growing problem].

Abstract

Normocalcemic primary hyperparathyroidism is at present one of the most common reasons for consultation in bone metabolism units. It is characterized by increased levels of intact parathyroid hormone in the presence of normal serum calcium (total and ionized) in generally asymptomatic individuals. The differential diagnosis should be considered in all situations that occur with secondary hyperparathyroidism. Its natural history is not well known, and it does not always progress to hypercalcemia. As a recently recognized entity, there are still no specific recommendations for its management. In this review we discuss some aspects of this entity, emphasizing the importance of a proper laboratory diagnosis, assessing possible signs or symptoms associated such as kidney stones or osteoporosis, which can help the clinician to take a conservative or interventionist attitude.

Keywords

Adenoma, Male, Hyperparathyroidism, Primary, Diagnosis, Differential, Fractures, Spontaneous, Parathyroid Neoplasms, Cardiovascular Diseases, Parathyroid Hormone, Asymptomatic Diseases, Disease Progression, Prevalence, Humans, Osteoporosis, Calcium, Female, Hyperparathyroidism, Secondary, Urinary Calculi, Vitamin D

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Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Top 10%
Average
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