
Genetic predisposition is of great importance among other risk factors of certain socially significant chronic non-inflammatory diseases. Changes in both nuclear and mitochondrial human genome may play a role in the development of these diseases. Recent studies have shown that mutations in the mitochondrial genome are associated with some diseases, such as type 2 diabetes, hypertension, and various types of cardiomyopathy. Maternal inheritance in some cases suggests that their cause may be precisely the defects of mitochondrial DNA.
Diabetes Mellitus, Type 2, Chronic Disease, Genome, Mitochondrial, Hypertension, Mutation, Humans, Cardiomyopathies, DNA, Mitochondrial
Diabetes Mellitus, Type 2, Chronic Disease, Genome, Mitochondrial, Hypertension, Mutation, Humans, Cardiomyopathies, DNA, Mitochondrial
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