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Feline herpesvirus 1, the causative agent of feline viral rhinotracheitis

Authors: Costes, Bérénice; Van Den Brande, A.; Thiry, Etienne; Vanderplasschen, Alain;

Feline herpesvirus 1, the causative agent of feline viral rhinotracheitis

Abstract

Les maladies respiratoires infectieuses connues sous le nom de « coryza » représentent l’un des domaines les plus importants en médecine féline. Les enquêtes épidémiologiques montrent que 80 % des cas sont dûs au calicivirus félin et à l’herpèsvirus félin 1 (FeHV-1). Le FeHV-1 est un alphaherpèsvirus très répandu dans la population féline et distribué dans le monde entier. Il est responsable de la rhinotrachéite virale féline. Cette infection peut se présenter sous forme aiguë, chronique ou latente. Elle est caractérisée par un syndrome fiévreux accompagné de troubles respiratoires et oculaires aigus dont les plus fréquents sont de la conjonctivite et de la kératite. Les cas graves peuvent évoluer vers la cécité surtout suite aux réactivations virales répétées. Les porteurs latents du virus sont importants d’un point de vue épidémiologique car ils représentent une source majeure d’infection pour les chats indemnes. À l’heure actuelle, aucun vaccin ne permet la prévention de l’infection. Au mieux, les vaccins disponibles permettent de réduire les signes cliniques sans pour autant empêcher l’établissement de la latence et la réactivation. C’est pourquoi, aujourd’hui encore, la rhinotrachéite virale féline reste un problème majeur chez le chat domestique. Dans cette revue, nous présentons les connaissances actuelles sur la rhinotrachéite virale féline et sur son agent étiologique, le FeHV-1.

Infectious respiratory diseases also called ‘cat flu’ are nowadays one of the most relevant areas of feline medicine. Epidemiologic surveys revealed that 80% of the cases are due to feline calicivirus and Felid herpesvirus 1 (FeHV-1). FeHV-1 is an alphaherpesvirus that has a worldwide distribution in cat population. It is responsible for feline viral rhinotracheitis. This disease can be acute, chronic or latent. It is characterized by fever and respiratory or ocular signs among which conjunctivitis and keratitis are the most common. Severe cases can cause complete blindness of the cat mostly following repetitive reactivations. Latent viral carriers are epidemiologically important because they are the main source of infection to susceptible cats. Nowadays no vaccine can prevent infection. At best, available vaccines help to reduce clinical signs but fail to prevent establishment of latency or reactivation. Consequently, feline viral rhinotracheitis still represents a major problem in domestic cats. This review focuses on the current knowledge about feline viral rhinotracheitis and its etiologic agent, FeHV-1.

Country
Belgium
Related Organizations
Keywords

Veterinary medicine & animal health, Sciences du vivant, Life sciences, Médecine vétérinaire & santé animale

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green