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The type three secretion system of Bordetella pertussis

Authors: Fennelly, Neil;

The type three secretion system of Bordetella pertussis

Abstract

Despite the description of whooping cough as a vaccine preventable disease, and the implementation of extensive vaccination programs, Bordetella pertussis remains a significant cause of childhood morbidity and mortality worldwide. The recent observation that increasing numbers of adults are being diagnosed with B. pertussis, and may be transmitting the bacteria to infants, has called into question the level of protection provided by current pertussis vaccines, and highlighted the need for a better understanding of the molecular mechanisms underlying B. pertussis pathogenesis. The identification of novel B. pertussis surface molecules that assist in the design of improved pertussis vaccines and the further characterisation of B. pertussis virulence factors are therefore important goals in the field of pertussis research. TARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie

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Ireland
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Keywords

Ph.D, 618, 616, Ph.D. Trinity College Dublin, Biochemistry, Ph.D., Biochemistry

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
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