The purpose of the antimicrobial stewardship is to make an effort so that it tries to draw out the maximum effect by using the antimicrobial agent and to decrease the risk of side-effect, and suppress the emergence of antimicrobial resistant organisms. Antimicrobial stewardship is an activity to achieve these goals. Antimicrobial stewardship must be regarded as quality control and risk management procedure in the medical institution. Enough authorization to medical staff by the executive of the hospital is indispensable for the achievement of proper use of antimicrobial agents. Additionally, the manager of the hospital should give enough resources to support this activity.