
In the present study, an activity of Bixa orellana extract against Leishmania amazonensis was demonstrated.Experimentally infected BALB/c mice were treated with B. orellana extract which showed a significant activity against promastigote and amastigote forms of L. amazonensis.This study supports the importance of natural sources as antileishmanial drugs.
Leishmania, Life Cycle Stages, Mice, Inbred BALB C, Cell Survival, Plant Extracts, Body Weight, Antiprotozoal Agents, Bixaceae, Inhibitory Concentration 50, Mice, Random Allocation, Amphotericin B, Macrophages, Peritoneal, Animals, Female, Leishmaniasis
Leishmania, Life Cycle Stages, Mice, Inbred BALB C, Cell Survival, Plant Extracts, Body Weight, Antiprotozoal Agents, Bixaceae, Inhibitory Concentration 50, Mice, Random Allocation, Amphotericin B, Macrophages, Peritoneal, Animals, Female, Leishmaniasis
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