[Th1, Th17 and Th1+17 cells].

T helper cells contribute to the induction and maintenance of rheumatic inflammation through the secretion of cytokines. The analysis of Th1 cells expressing interferon-γ, Th17 cells expressing interleukin-17 and the newly described Th1+17 cells could give insight into the pathophysiological mechanisms of rheumatic diseases. This could lead to the development of novel, targeted therapeutic strategies.

Related Organizations

Leibniz Association
Germany
German Rheumatism Research Centre
Germany

Keywords

Rheumatic Diseases, Models, Immunological, Animals, Cytokines, Humans, Th17 Cells, Th1 Cells, Immunity, Innate

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