[Valine substitution].
Copyright policy [Valine substitution].
The review deals with analysis of the literature data concerning the importance of valine substitution in certain proteins, namely p21 ras and hemoglobin. A model of the active site of p21 protein is discussed in the light of GTPase activities alterations as a result of monoaminoacid substitution in conservative sites of p21 protein. The established relationship between some forms of transformation and Plasmodium falciparum malaria on the molecular level is shown in a new aspect. The widespread opinion that Hb S is valid as the means of malaria resistance is questioned in terms of new molecular data.
Binding Sites, Hydrolysis, Molecular Sequence Data, Valine, Oncogene Protein p21(ras), Malaria, Cell Transformation, Neoplastic, Sequence Homology, Nucleic Acid, Mutation, Animals, Humans, Amino Acid Sequence, Guanosine Triphosphate, Phosphorylation
Binding Sites, Hydrolysis, Molecular Sequence Data, Valine, Oncogene Protein p21(ras), Malaria, Cell Transformation, Neoplastic, Sequence Homology, Nucleic Acid, Mutation, Animals, Humans, Amino Acid Sequence, Guanosine Triphosphate, Phosphorylation
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!