We examined the correlation between the visual field index (VFI) and mean deviation (MD), as well as the correlation on VFI slope and MD slope.This retrospective study was performed on 105 eyes of 60 patients. All eyes underwent examination by the Humphrey visual field analyzer. The correlation of the (i) VFI and MD, (ii) VFI slope and MD slope were analyzed in all eyes and the eyes were classified by visual field patterns (paracentral, peripheral, mixed and normal defect type). (iii) The agreement degree between the VFI slope and MD slope was examined. A generalized-estimating-equation(GEE) model and kappa statistic were used for analysis.A significant correlation between MD and VFI was shown in all eyes, including eyes classified of visual field defect. The correlation between the VFI slope and MD slope was significant in all eyes. However, these correlations were not evident in paracentral type of defect but in the other types. K statistic evaluated a moderate agreement between the VFI slope and MD slope.A significant correlation was shown between the VFI and MD, VFI slope and MD slope in all eyes. However, no correlation between the VFI slope and MD slope existed in the paracentral area. It seems that the evaluation of progression of visual field defect in the central area needs to be considered carefully.