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Análisis de la heteroplasmia y la variación genética del ADNmt en la centolla Maja brachydactyla, Balss 1922

Analysis of heteroplasmy and genetic variation of mtDNA in spider crab Maja brachydactyla, Balss 1922
Authors: Fernández Pujó, Wendy;

Análisis de la heteroplasmia y la variación genética del ADNmt en la centolla Maja brachydactyla, Balss 1922

Abstract

[Resumen]: La heteroplasmia mitocondrial es un fenómeno por el cual dos secuencias diferentes de ADN mitocondrial coexisten en una misma célula o individuo. Recientemente se ha descubierto una alta incidencia de este fenómeno en la centolla (Maja brachydactyla Balss, 1922) en una población de Galicia. Se creía que el origen de esta heteroplasmia podría estar relacionada con cruces interespecíficos entre Maja brachydactyla y Maja squinado al sur de la Península Ibérica. Estas hibridaciones provocarían fallos en los sistemas de eliminación de las mitocondrias paternas generándose heteroplasmia. Además, se debería formar un gradiente positivo N-S de incidencia de heteroplasmia a lo largo de la costa europea. Sin embargo, los resultados de este estudio rechazan la hipótesis al no encontrar una incidencia menor en una región más al norte no Galicia. Por tanto, se plantea la posibilidad de que estos fallos deban a errores en los mecanismos de eliminación de las mitocondrias paternas provocados por un factor desconocido. Además, debido a la elevada diversidad detectada y la ausencia de zonación en las redes haplotípicas, se ha detectado que esta especie se comporta como una única unidad de apareamiento aleatoria en el Atlántico norte.

[Abstract]: Mitochondrial heteroplasmy is a phenomenon by which two different mitochondrial DNA sequences coexist in the same cell or individual. A high incidence of this phenomenon has recently been discovered in the spider crab (Maja brachydactyla Balss, 1922) in a population of Galicia. It was believed that the origin of this heteroplasmy could be related to interspecific crosses between Maja brachydactyla and Maja squinado in the south of the Iberian Peninsula. These hybridizations would cause failures in the paternal mitochondria elimination systems, generating heteroplasmy. In addition, a positive N-S gradient of heteroplasmy incidence should form along the European coast. However, the results of this study reject the hypothesis by not finding a lower incidence in a region further north than Galicia. Therefore, the possibility arises that these failures are due to errors in the mechanisms of elimination of paternal mitochondria caused by an unknown factor. In addition, due to the high diversity detected and the absence of zonation in the haplotype networks, it has been detected that this species behaves as a single random mating unit in the North Atlantic.

Traballo fin de mestrado (UDC.CIE). Bioloxía mariña. Curso 2021/2022

Country
Spain
Related Organizations
Keywords

Maja, Centollos, Marcadores genéticos, ADN mitocondrial, Genética, Atlántico Norte, Mutación en los animales, Genética de poblaciones, Análisis, Animales, Variabilidad genética, Mutagénesis, Poblaciones

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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