
handle: 2183/27205
[Resumen]: El proyecto que se propone tiene como principal objetivo la evaluación de la actividad antibiótica de extractos hidroalcohólicos obtenidos a partir de tres especies vegetales de uso medicinal tradicional (Pseudoscleropodium purum, Cladonia arbuscula y Cytisus scoparius) en cultivos de Escherichia coli y Staphylococcus aureus. Además, la propuesta plantea la evaluación de la posible actividad sinérgica de los extractos en combinación con antibióticos de habitual uso clínico contra infecciones causadas por estas especies bacterianas. Con el fin de obtener información sobre la composición de los extractos, se propone realizar un análisis preliminar de los mismos mediante HPLC-DAD-MS.
[Abstract]: The proposed project has as main objective the evaluation of the antibiotic activity of hiroalcholic extracts obtained from three vegetal species of traditional medical use (Pseudoscleropodium purum, Cladonia arbuscula and Cytisus scoparius) in cultures of Escherichia coli and Staphylococcus aureus. Moreover, the proposal raises the evaluation of the possible synergistic activity of the extracts in combination with habitual clinical use antibiotics against infections caused by this bacterial species. With the purpose of obtaining information about the composition of the extracts, it is proposed to perform a preliminary analysis of these through HPLC-DAD-MS.
Traballo fin de grao (UDC.CIE). Bioloxía. Curso 2019/2020
HPLC-DAD-MS, Antibiotic resistance, Phytopharmacology, Secondary metabolites, Actividad antibiótica, Metabolitos secundarios, Plant extracts, Nuevos antibióticos, Synergistic activity, Antibiotic activity, Fitofarmacología, Actividad sinérgica, Resistencia antibióticos, Extractos vegetales, New antibiotics
HPLC-DAD-MS, Antibiotic resistance, Phytopharmacology, Secondary metabolites, Actividad antibiótica, Metabolitos secundarios, Plant extracts, Nuevos antibióticos, Synergistic activity, Antibiotic activity, Fitofarmacología, Actividad sinérgica, Resistencia antibióticos, Extractos vegetales, New antibiotics
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