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Historia y decadencia de los antibióticos: la fagoterapia como alternativa

Historia e decadencia dos antibióticos: a fagoterapia como alternativa
Authors: Fondo Pérez, Christian;

Historia y decadencia de los antibióticos: la fagoterapia como alternativa

Abstract

[Resumen]: Los antibióticos han sido desde hace décadas los fármacos más revolucionarios, pudiendo curar todo tipo de enfermedades y reduciendo la mortalidad de forma significativa. Sin embargo, a pesar de todos los avances en su producción, su efecto se ha ido deteriorando de forma paulatina hasta llegar a la crisis actual. La resistencia a antibióticos se ha convertido en un problema a escala global, llegando a causar 700.000 muertes al año y pérdidas económicas millonarias. Esta crisis deriva de varios factores como el uso excesivo de los antibióticos por parte de personas y ganaderos, las prescripciones incorrectas y la falta de investigación sobre dichos antimicrobianos. Esta decadencia de los antibióticos ha motivado al descubrimiento de una serie de alternativas, entre ellas el uso de bacteriófagos (virus especializados en matar bacterias), para curar infecciones de bacterias multirresistentes. Este tratamiento presenta la seguridad y eficacia necesaria para convertirse en nuestra mejor arma contra las bacterias, siendo la solución al problema de los antibióticos que como veremos aun tendrán su lugar en la lucha contra los microorganismos junto con los virus en los tratamientos mixtos

[Resumo]: Os antibióticos foron desde fai décadas os fármacos máis revolucionarios, sendo capaces de curar todo tipo de enfermedades e reducindo a mortalidade de forma significativa. Sen embargo, a pesar de tódolos avance na súa producción, o se efecto foise deteriorando de forma paulatina ata chegar á crise actual. A resistencia a antibióticos converteuse nun problema a escala global, chegando a causa 700.000 mortes ao ano e pérdidas económicas millonarias. Esta crise deriva de varios factores como o uso excesivo dos antibióticos por parte de persoas e gandeiros, as prescripcións incorrectas e a falta de investigación sobre ditos antimicrobianos. Esta decadencia dos antibióticos motivou o descubrimento dunha serie de alternativas, entre elas o uso de bacteriófagos (virus especializados en matar bacterias), para curar infeccións de bacterias multirresistentes. Este tratamento presenta a seguridade e eficacia necesarias para converterse na nosa mellor arma contra as bacterias, sendo a solución ó problema dos antibióticos que como veremos aínda terán o seu lugar na loita contra contra os microorganismos xunto cos virus nos tratamentos mixtos.

[Abstract]: Antibiotics have beenthe most revolutionary drugs for decades, being able to cure all kinds of diseases and reducing mortality significantly. However, despite all the advances in its production, its effect has been gradually deteriorating until reaching the current crisis. Antibiotic resistance has become a problema on a global scale, causing 700.000 deaths a year and economics losses in the millions. This crisis derived from various factors such as the overuse of antibiotics by people and the livestock industry, incorrect prescriptions and the lack of research on these antimicrobials. This declina in antibiotics had led to the discovery of a number of alternatives, including the use of bacteriophages (viruses specialized in killing bacterias), to cure infections of multi-resistent bacteria. This treatment presents the safety and efficacy necessary to become our best weapon against bacterias, being the solution to the problema of antibiotics which, as we will see, will still have a place in the fight against microorganisms along with the viruses in mixed treatments.

Traballo fin de grao (UDC.CIE). Bioloxía. Curso 2019/2020

Country
Spain
Related Organizations
Keywords

Crise, Treatment, Fagoterapia, Tratamento, Phage therapy, Resistencia, Antibiotics, Resistance, Tratamiento, Antibióticos, Crisis

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green