[Sperm DNA damage and unexplained recurrent spontaneous abortion].
Copyright policy )[Sperm DNA damage and unexplained recurrent spontaneous abortion].
To explore the relationship of sperm DNA damage with unexplained recurrent spontaneous abortion (URSA).Sperm DNA fragmentation was evaluated by sperm chromatin dispersion (SCD), and the results were expressed in terms of DNA fragmentation index (DFI). DFIs were measured in the male partners of 56 women with URSA (the experiment group) and of 31 without URSA (the control group).The DFI was shown to be (11.0% - 56.9%) in the experiment group, 21 (37.5%) of the subjects over 30%, as compared with (10.0% -36.8%) in the control group, only 8 (25.8%) of the subjects over 30%, significantly higher in the former than in the latter (29.4% vs 25.5%, P < 0.05).There is a relationship between sperm DNA damage and URSA.
- PLA Navy General Hospital China (People's Republic of)
Adult, Male, Abortion, Habitual, Pregnancy, Case-Control Studies, Humans, Female, DNA Fragmentation, Spermatozoa, DNA Damage
Adult, Male, Abortion, Habitual, Pregnancy, Case-Control Studies, Humans, Female, DNA Fragmentation, Spermatozoa, DNA Damage
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