This entry begins with a brief description of the historical roots and emergence of the concept of symmetry that is at work in modern science. It then turns to the application of this concept to physics, distinguishing between two different uses of symmetry: symmetry principles versus symmetry arguments. It mentions the different varieties of physical symmetries, outlining the ways in which they were introduced into physics. Then, stepping back from the details of the various symmetries, it makes some remarks of a general nature concerning the status and significance of symmetries in physics.