Experiences with HEK293: A Human Cell Line.

Michael J, Rubino

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PDA Journal of Pharm...arrow_drop_down

PDA Journal of Pharmaceutical Science and Technology

Article . 2016

Data sources: Europe PubMed Central

Experiences with HEK293: A Human Cell Line.

descriptionPublicationkeyboard_double_arrow_right Article 22 Apr 2016 English Journal:PDA journal of pharmaceutical science and technology, volume 64 (issn: 1948-2124,

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Authors: Michael J, Rubino;

pmid: 21502043

Experiences with HEK293: A Human Cell Line.

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Abstract

The paper describes considerations taken with regard to a recombinant human cell line (HEK293) producing a therapeutic protein. When working with HEK293 cells, besides standard viral safety issues, special precautions should be taken because this cell line is susceptible to infection by numerous viruses. A viral contamination event occurred with this cell line even after a number of precautions were taken.

Keywords

HEK293 Cells, Viruses, Humans, Cell Line

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