Exfoliation glaucoma is a specific type of glaucoma secondary to exfoliation syndrome. Exfoliation syndrome is one of the most common identifiable causes of secondary open-angle glaucoma worldwide. In recent years, great progress has been made in exfoliation syndrome and exfoliation glaucoma. The study of exfoliation glaucoma in the aspects of prevalence, inheritance, formation of exfoliative material, gene analysis and treatment are reviewed in this article.