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[The role of extracellular ATP in the airway].

Authors: Hong-Mei, Guo; Yu-Li, Luo; Wen-Liang, Zhou;

[The role of extracellular ATP in the airway].

Abstract

ATP serves not only as an energy source for all cell types but as an extracellular messenger for autocrine and paracrine signaling involving in a versatile role in modulating various cellular functions. This review summarizes the efflux pathways of ATP released from airway epithelial cells, the signal pathways through which ATP induces ion transport by the epithelia of airway, as well as its epithelium-dependent modulation of smooth muscle contraction of airway and the mechanism underlying in airway diseases.

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Keywords

Inflammation, Ion Transport, Respiratory System, Epithelial Cells, Muscle, Smooth, Pulmonary Edema, Adenosine Triphosphate, Mucociliary Clearance, Respiratory Physiological Phenomena, Animals, Humans, Extracellular Space, Muscle Contraction

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
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