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Hong Kong Medical Journal
Article . 2013
Data sources: Europe PubMed Central
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HKU Scholars Hub
Article . 2011
Data sources: HKU Scholars Hub
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Claim

Targeting glutamate synthase for tuberculosis drug development.

descriptionPublicationkeyboard_double_arrow_right Article 24 May 2011 China (People's Republic of) English Publisher:Hong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/index.htmlJournal:Hong Kong medical journal = Xianggang yi xue za zhi, volume 17 Suppl 2 (issn: 1024-2708, Copyright policy )
Authors: Tanner, JA; Cheung, YW;

pmid: 21368333

handle: 10722/133579

Targeting glutamate synthase for tuberculosis drug development.

Abstract

1. The Mycobacterium tuberculosis glutamate synthase consisting of alpha and beta subunits can be purified in a heterologous Escherichia coli expression system. 2. The beta subunit can be expressed in the soluble protein fraction under low temperature conditions. 3. The alpha subunit enters inclusion bodies in E coli but can be refolded and subsequently purified.

published_or_final_version

Country
China (People's Republic of)
Related Organizations
Keywords

Cloning, Organism, Glutamate Synthase, Gene Expression, Humans, Tuberculosis, Mycobacterium tuberculosis, Sequence Analysis, DNA, Polymerase Chain Reaction

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 5
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
Green
gold