To optimize the structural behaviour of Concrete-Filled Steel Tube (CFST) beams subjected to bending, this study conducted a detailed analysis through numerical simulations and experimental data. CFST beams combine the strength and ductility of steel with the stability of concrete, offering an efficient solution for modern structural applications. The study is part of a research project developed at the School of Industrial Engineering of Barcelona (ETSEIB) and includes a prior experiment involving four-point monotonic bending tests on three CFST samples. These experiments measured displacements and deflections to provide essential data for validating the numerical model. The main objective of this work is to develop and validate a parametric finite element model using ANSYS Mechanical APDL. This model allows for the analysis of how key parameters, such as yield stress, compressive stress, and the distance between supports and loads, influence the structural performance of CFST beams. The simulation results were compared with experimental data to ensure the reliability of the model, and with theoretical analyses based on the principles of material strength to achieve a comprehensive understanding. The factors studied include principal stresses, von Mises stresses, initial stiffness, buckling, and the position of the neutral axis, determining optimal configurations to maximize structural performance. This research provides key insights for future applications of CFST beams in high-rise buildings and other infrastructures, contributing to the development of more precise and sustainable models in structural engineering.