On the basis of job characteristics of workers from the production "ethylene", chronometric studies and measurement of concentration from chemical compounds are developed professional diagrams and risk diagrams, which give a possibility for more precise account of the exposure to chemical noxious compounds (by figures). According to the values of the estimated total index of exposure 156 workers are distributed in 5 groups. Besides, 48 workers with prolonged length of service in the production and 37 persons control group are examined. The toxicological, haematological and biochemical indices are studied and the neuro-vegetative status traced. Mainly in the groups with high chemical exposure (first and second risk groups) and with prolonged length of service are established high per cent of workers with deviation in the examined indices, which give grounds to assert for the presence of dose-response relationship.