
In accordance with the Pharmacopoeia of the GDR, from multiple-dose containers containing injection preparations with preservatives added such preparations may be repeatedly withdrawn up to 72 h after opening these containers. Exempted from this limitation are multiple-dose containers containing insulin injection preparations repeatedly used by diabetics for self-injections. Microbiological tests were to contribute to clearing the question whether the period of using these insulin multiple-dose containers can be provided to be maximally 30 d after first use.
Preservatives, Pharmaceutical, Colony Count, Microbial, Humans, Insulin, Drug Contamination, Drug Packaging
Preservatives, Pharmaceutical, Colony Count, Microbial, Humans, Insulin, Drug Contamination, Drug Packaging
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