[Inhibitory effects of LHRH on LH receptors in the rat testis].

C, Auclair; L, Ferland; L, Cusan; P A, Kelly; F, Labrie; G, Azadian-Boulanger; J P, Raynaud

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Article . 1978

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[Inhibitory effects of LHRH on LH receptors in the rat testis].

descriptionPublicationkeyboard_double_arrow_right Article 25 Sep 1978 French Journal:Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, volume 286

Authors: C, Auclair; L, Ferland; L, Cusan; P A, Kelly; F, Labrie; G, Azadian-Boulanger; J P, Raynaud;

pmid: 208798

[Inhibitory effects of LHRH on LH receptors in the rat testis].

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Abstract

A single injection of LHRH to the adult male rat, as of its analog [D-Ala6, des-Gly-NH102] LHRH ethylamide, resulted in a marked decrease in LH receptors in the tests. Plasma testosterone level and the weight of the seminal vesicles and prostate were also decreased after treatment. These data demonstrate that LHRH can decrease the sensitivity of LH receptors and testicular function in the rat.

Keywords

Gonadotropin-Releasing Hormone, Male, Testis, Prostate, Animals, Seminal Vesicles, Receptors, Cell Surface, Testosterone, Organ Size, Hormones, Rats

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