From 1985 to 1987, the authors performed Nd:YAG laser vitreolysis in 20 eyes with vitreous membranes. The average power used was 27 mJ, and the maximum was 65 mJ. 18 eyes with vitreous strands were relieved or partially relieved. 2 eyes with floating vitreous membranes were not helped. Vision was improved in 11 eyes, unchanged in 8 eyes, and worsened in 1 eye. The complications included local opacification of the crystalline lens in 2 eyes, retinal hemorrhage in 2 eyes, and retinal hole in 1 eye. It was concluded that YAG laser was useful for lysis of organized vitreous membranes near the optical axis of the eye, and the effect should be good with appropriate contact lenses and proper selection of candidates for the operation.