
pmid: 2060690
handle: 2434/201115
An investigation was carried out into the possible effects of ampicillin and a sulbactam/ampicillin combination on the immune system of healthy subjects. The following immunological variables were compared before and after antibiotic therapy: proliferation response of peripheral mononuclear cells to phytohaemagglutinin; variation of T- and B-lymphocytes; dosage of interleukin-2; and production of immunoglobulin A. The data obtained did not demonstrate any immunodepressive activity by either ampicillin or the sulbactam/ampicillin combination.
Adult, Male, Adolescent, In Vitro Techniques, Middle Aged, Lymphocyte Activation, Immunoglobulin A, Sulbactam, Immune System, Humans, Interleukin-2, Ampicillin, Drug Therapy, Combination, Female
Adult, Male, Adolescent, In Vitro Techniques, Middle Aged, Lymphocyte Activation, Immunoglobulin A, Sulbactam, Immune System, Humans, Interleukin-2, Ampicillin, Drug Therapy, Combination, Female
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