[Molecular targeted therapies].
Copyright policy )[Molecular targeted therapies].
Current treatment paradigms in cancer patients are shifting from cytotoxic chemotherapies alone to single-agent and combination biological and targeted therapies. Targeted therapies are entering standard treatment paradigms. As patient responses to targeted therapies vary, predictive biomarkers will be an important tool of a patient's diagnostic workup in personalized medicine. This review provides a broad overview of molecular targeted agents, and highlight biomarkers, including novel adaptive clinical trial designs, incorporating putative biomarkers into prospective clinical trials.
- Kindai University Japan
Clinical Trials as Topic, Antibodies, Monoclonal, Angiogenesis Inhibitors, Protein-Tyrosine Kinases, Antibodies, Monoclonal, Humanized, Bevacizumab, Antibodies, Monoclonal, Murine-Derived, Drug Design, Neoplasms, Antigens, Surface, Biomarkers, Tumor, Humans, Enzyme Inhibitors, Rituximab
Clinical Trials as Topic, Antibodies, Monoclonal, Angiogenesis Inhibitors, Protein-Tyrosine Kinases, Antibodies, Monoclonal, Humanized, Bevacizumab, Antibodies, Monoclonal, Murine-Derived, Drug Design, Neoplasms, Antigens, Surface, Biomarkers, Tumor, Humans, Enzyme Inhibitors, Rituximab
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