A successful weight loss program leads to a new metabolic and endocrine balance that needs new long term management. Recent researches have shown some predictors as well as some barriers of the long term weight management. Predictors and barriers are linked to the lost weight, to the subject's habits and to the patient's psychosocial sphere. During the four-year follow-up, 78% of patients maintained 10% or more of their initial weight loss. The patients who maintained their weight presented less binge eating disorder, good motivation in diet and physical activity.