Novel t(15;19)(q15;p13) chromosome abnormality in a thymic carcinoma.

A 22-year-old female with a thymic carcinoma is reported. The tumor was refractory to both chemotherapy and irradiation. The patient died with an aggressive clinical course. Cytogenetic study showed that the tumor cells had a chromosome translocation, t(15;19)(q15;p13), which was not identified previously in human cancer.

Related Organizations

Kochi Medical School Hospital
Japan

Keywords

Adult, Chromosomes, Human, Pair 15, Karyotyping, Humans, Female, Thymus Neoplasms, Chromosomes, Human, Pair 19, Mediastinal Neoplasms, Translocation, Genetic

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