[Immunoenzyme technique for detection of salivary anti-diphtheria antibacterial antibodies].
Copyright policy )[Immunoenzyme technique for detection of salivary anti-diphtheria antibacterial antibodies].
Enzyme immunoassay for determining salivary anti-diphtheria antibacterial IgA was developed to evaluate local anti-diphtheria immunity. One hundred and thirty-one apparently healthy preschool and school children aged 2 to 16 years, inoculated with diphtheria and tetanus toxoids and pertussis and attenuated diphtheria and tetanus toxoid vaccines by the immunization schedules. The apparently healthy children's saliva were found to have anti-diphtheria antibacterial sIgA, the mean content of which in the examinees aged 2-16 years was 49.4 +/- 3.0 units/ml and depended on age. The level of antibacterial anti-diphtheria sIgA significantly increased in children by age 7-9 years and unchanged by 16 years of age. Comparison of sIgA levels in children with diphtheria morbidity could identify 2-6-year-old children as a diphtheria infection risk group.
Immunoenzyme Techniques, Adolescent, Child, Preschool, Humans, Diphtheria, Child, Saliva, Antibodies, Bacterial, Immunity, Mucosal, Immunoglobulin A
Immunoenzyme Techniques, Adolescent, Child, Preschool, Humans, Diphtheria, Child, Saliva, Antibodies, Bacterial, Immunity, Mucosal, Immunoglobulin A
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