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Alloxan diabetes.

Authors: Houssay, Bernardo Alberto;

Alloxan diabetes.

Abstract

The intravenous injection of alloxan induces a triphasic modification of the blood sugar level; (a) initial hiperglicemia; (b) secondary hypoglycemia; and (c) final hyperglycemia. The liver is essential for the initial hyperglycemia since this does not appear in hepatectomized dogs or toads or in eviscerated dogs. The initial hyperglycemia was observed in dogs after splanchnicectomy in adrenalectomized dogs or toads but not in adrenalectomized rats. In the dog the injection of alloxan produces a rise in blood pressure which is not due to the liberation of adrenaline as shown by suprareno-jugular anastomosis (Houssay and Rapela, unpublished data).

Fil: Houssay, Bernardo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina

Unidad documental simple

TIBYME

papel

Country
Argentina
Keywords

BLOOD SUGAR LEVEL, ALLOXAN, HOUSSAY EL INVESTIGADOR, PUBLICACIONES CIENTIFICAS, EL INVESTIGADOR, Diabetes Mellitus, Experimental, HYPOGLYCEMIA, https://purl.org/becyt/ford/6.3, PUBLICACIONES, HYPERGLYCEMIA, https://purl.org/becyt/ford/3.1, Alloxan, https://purl.org/becyt/ford/6, Animals, DIABETES, HOUSSAY, BERNARDO A., https://purl.org/becyt/ford/3

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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
7
Average
Top 10%
Average
Green