Premature ventricular contractions (PVCs) are frequently encountered, and management is determined by symptoms, precipitating factors, and the presence of underlying cardiac disease. No treatment is indicated in patients with asymptomatic PVCs in absence of cardiac disease. Symptomatic patients without cardiac disease may be managed by identifying and correcting reversible causes. In patients with cardiac disease, management includes treating the underlying cardiac disease to improve both symptoms and prognosis.