[Advances in the study of regulation of novel organic cation transporter-2].
Copyright policy )[Advances in the study of regulation of novel organic cation transporter-2].
Novel organic cation transporter-2 (OCTN2), a member of the organic cation transporter family, may transport carnitine and multiple organic cationic drugs. Thus OCTN2 possesses substantial roles in physiology and pharmacology. A number of researches have proven that many factors can regulate the expression and/or function of OCTN2 via different pathways, and then may affect the homeostasis and disposition of drugs. This paper reviews recent progresses in this field.
- Jinan Central Hospital China (People's Republic of)
Organic Cation Transport Proteins, Membrane Proteins, Biological Transport, Colitis, Carnitine, Mutation, Animals, Homeostasis, Humans, PPAR alpha, Clofibrate, RNA, Messenger, Carrier Proteins, Solute Carrier Family 22 Member 5
Organic Cation Transport Proteins, Membrane Proteins, Biological Transport, Colitis, Carnitine, Mutation, Animals, Homeostasis, Humans, PPAR alpha, Clofibrate, RNA, Messenger, Carrier Proteins, Solute Carrier Family 22 Member 5
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