[Anti-ulcerative effect of non-starch polysaccharides].
Copyright policy )[Anti-ulcerative effect of non-starch polysaccharides].
Standard models of experimental ulceration (of neurogenic origin, H. Shay ulcer, indomethacine-, ethanol-, prednisolone-, histamine- and acetate-induced ulcers) were used to demonstrate protective effect of non-starch polysaccharides (potassium alginate, potassium pectate, low-esterified pectin). Potassium pectate proved to be the most efficacious protector. Mechanism of its anti-ulcerative action is attributable to antacidic, cytoprotective, and reparative activity. It appeals to optimally stimulate the motor-evacuation function and, besides, exhibits marked anti-inflammatory activity.
Male, Drug Carriers, Alginates, Hexuronic Acids, Administration, Oral, Biocompatible Materials, Rats, Disease Models, Animal, Mice, Treatment Outcome, Gastric Emptying, Glucuronic Acid, Polysaccharides, Animals, Pectins, Female, Stomach Ulcer, Rats, Wistar, Antidiarrheals
Male, Drug Carriers, Alginates, Hexuronic Acids, Administration, Oral, Biocompatible Materials, Rats, Disease Models, Animal, Mice, Treatment Outcome, Gastric Emptying, Glucuronic Acid, Polysaccharides, Animals, Pectins, Female, Stomach Ulcer, Rats, Wistar, Antidiarrheals
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