Asymmetric synthesis of alpha-tocopherol.

Hengartner, Urs; Chougnet, Antoinette; Liu, Kegang; Woggon, Wolf-D.

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Chemistry - A European Journal

Article . 2010

Data sources: Europe PubMed Central

SONAR - Swiss Open Access Repository

Article . 2010

Data sources: SONAR - Swiss Open Access Repository

Asymmetric synthesis of alpha-tocopherol.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2010 Switzerland English Publisher:Wiley-VCH VerlagJournal:Chemistry (Weinheim an der Bergstrasse, Germany), volume 16 (issn: 1521-3765,

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Authors: Hengartner, Urs; Chougnet, Antoinette; Liu, Kegang; Woggon, Wolf-D.;

pmid: 20013765

Asymmetric synthesis of alpha-tocopherol.

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Abstract

Alpha-tocopherol was synthesized from a chiral intermediate alpha-hydroxy ester by means of two ring-closing methods to yield the chromanol in 94% diastereomeric excess.

Country

Switzerland

Related Organizations

University of Basel
Switzerland

Keywords

Cyclization, alpha-Tocopherol, Stereoisomerism, Chromans

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