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Autoanticuerpos preformados en la pérdida precoz del trasplante renal

Authors: Mora Díaz, Sergio;

Autoanticuerpos preformados en la pérdida precoz del trasplante renal

Abstract

El trasplante renal es la mejor opción terapéutica para la enfermedad renal terminal (ERT); el conocimiento del papel de los anticuerpos anti-antígeno leucocitario humano (HLA) en el rechazo a corto y largo plazo, junto con el descubrimiento de los inmunosupresores anti-calcineurínicos, ha permitido disminuir la pérdida temprana del injerto renal. Aun así, todavía existen pacientes que pierden precozmente el injerto principalmente por trombosis, habiéndose descrito anticuerpos frente a antígenos autólogos en el rechazo y pérdida del injerto a largo plazo. Sin embargo no se conoce su papel en la pérdida temprana del injerto. Objetivo: El principal objetivo de este estudio es determinar el papel de una serie de autoanticuerpos preformados y marcadores de daño endotelial en la pérdida del injerto en los primeros 6 meses post-trasplante y entre los 7 y 24 meses post-trasplante...

Country
Spain
Related Organizations
Keywords

Nefrología y urología, Riñones, 616.61‑089.843(043.2), Kydneys

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
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