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Prevalencia de fibrosis hepática detectada con elastografía de vibración controlada y su relación con eventos cardiovasculares en pacientes con diabetes mellitus tipo 2 atendidos en un establecimiento privado de tercer nivel en el periodo del 2016 al 2023

Authors: Laurencio Melgarejo, Lucy Melina; Ortega Vela, Xiomara Sheissy; Humpire Mamani, Vladimir Jossias;

Prevalencia de fibrosis hepática detectada con elastografía de vibración controlada y su relación con eventos cardiovasculares en pacientes con diabetes mellitus tipo 2 atendidos en un establecimiento privado de tercer nivel en el periodo del 2016 al 2023

Abstract

Antecedentes: La población más prevalente dentro de la enfermedad de hígado graso no alcohólico (NAFLD) son los diabéticos tipo 2 siendo los más susceptibles al desarrollo de fibrosis hepática avanzada. No se ha establecido claramente la asociación entre fibrosis hepática y el desarrollo de eventos cardiovasculares en los pacientes con NAFLD. Objetivos: Determinar la prevalencia de fibrosis hepática detectada con elastografía de vibración controlada y su relación con la presencia de evento cardiovascular (accidente cerebrovascular, infarto de miocardio y enfermedad arterial periférica) en pacientes con diabetes mellitus tipo 2. Materiales y métodos: Series de casos. Se revisó historias clínicas de pacientes diabéticos que contaban con resultado de Fibroscan ® de la Clínica Ricardo Palma en el periodo 2016-2023. Los datos clínicos y los resultados del Fibroscan ® fueron registrados en Microsoft Excel y posteriormente trasladados al software SPSS V.25.0 para el análisis estadístico. Resultados: Los datos de 100 pacientes con NAFLD y diabetes mellitus tipo 2 fueron analizados. La frecuencia de fibrosis hepática avanzada y evento cardiovascular fue de 32% y 11% respectivamente. El coeficiente de correlación de Fisher entre fibrosis avanzada y evento cardiovascular fue significativo con un 0,034. Conclusión: Existe correlación entre fibrosis avanzada y evento cardiovascular en pacientes con diabetes mellitus tipo 2.

Background: The most prevalent population within non-alcoholic fatty liver disease (NAFLD) are type 2 diabetics, who are most susceptible to the development of advanced liver fibrosis. The association between liver fibrosis and the development of cardiovascular events in patients with NAFLD has not been clearly established. Objectives: To determine the prevalence of liver fibrosis detected through controlled vibration elastography and its relationship with the presence of cardiovascular events (stroke, myocardial infarction, and peripheral arterial disease) in patients with type 2 diabetes mellitus. Materials and methods: Case series. Clinical records of diabetic patients with Fibroscan ® results from the Ricardo Palma clinic were reviewed for the period 2016-2023. Clinical data and Fibroscan ® results were recorded in Microsoft Excel and subsequently transferred to SPSS V.25.0 software for statistical analysis. Results: Data from 100 patients with NAFLD and type 2 diabetes mellitus were analyzed. The frequency of advanced liver fibrosis and cardiovascular events was 32% and 11%, respectively. Fisher's correlation coefficient between advanced fibrosis and cardiovascular events was significant at 0.034. Conclusions: There is a correlation between advanced fibrosis and cardiovascular events in patients with type 2 diabetes mellitus.

Country
Peru
Keywords

http://purl.org/pe-repo/ocde/ford#3.02.12, Evento Cardíaco Adverso, Enfermedad de Hígado Graso No Alcohólico, Fibrosis Hepática, Diabetes Mellitus Tipo 2, http://purl.org/pe-repo/ocde/ford#3.02.19, http://purl.org/pe-repo/ocde/ford#3.02.18, Técnica de Imagen Elastografíca, http://purl.org/pe-repo/ocde/ford#3.02.04

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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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impulse
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