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TBARS, glutathione and carnitine levels in human brain tumours

Authors: Sönmez, Hüseyin; Öztürk, Zeynep; Ekmekçi, Hakan; Tüzgen, Saffet; Kökoğlu, Emine;

TBARS, glutathione and carnitine levels in human brain tumours

Abstract

Amaç: Bu çalışmamızın amacı insan beyin tümörlerinde insan beyin tümörlerinde lipid peroksidasyonu (TBARS: thiobarbituric acid reactive substance) karnitin ve indirgenmiş glutatyon (GSH) düzeylerini tayin etmekti. Bulgular: Ortalama karnitin, GSH ve TBARS-2 düzeyleri tümörlü grupta sırasıyla 0.011±0.0047 mg/mg protein, 0.03±0.01 mg/mg protein ve 2.3±1.3 mmol/mg protein, normal beyin dokularında ise sırasıyla 0.019±0.002 mg/mg protein, 0.0387±0.01 mg/mg protein ve 0.62±0.2 mmol/mg protein bulundu.Kontrol grubuna göre insan beyin tümörlerinde karnitin ve GSH düzeyleri anlamlı olarak düşük (p<0.001, p<0.05) bulundu. TBARS düzeylerinin ise insan beyin tümörlerinde kontrol grubuna göre anlamlı olarak yüksek olduğu bulundu (p<0.001).Sonuç: Kanaat olarak; insan beyin tümörlerinde TBARS düzeylerinin artması karnitin ve GSH düzeylerindeki azalmaya bağlı olabilir.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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