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Hipernatremia como factor pronóstico de mortalidad en trauma encefalocraneano severo

Authors: Vásquez Tirado , Gustavo Adolfo; Vásquez Tirado, Gustavo Adolfo;

Hipernatremia como factor pronóstico de mortalidad en trauma encefalocraneano severo

Abstract

INTRODUCCION: El trauma craneoencefálico severo es una patología frecuente, conlleva una morbimortalidad no despreciable. La hipernatremia podría considerarse un factor asociado a mal pronóstico con el fin de optimizar la terapéutica en el grupo de pacientes de alto riesgo. OBJETIVO: Determinar si la hipernatremia es un factor pronóstico de mortalidad en pacientes con trauma craneoencefálico en un hospital público que es centro de referencia local en trauma. MATERIAL Y MÉTODO: Se realizó muestreo no probabilístico de pacientes con trauma encefalocraneano severo, adultos, ambos sexos de la Unidad de Cuidados Intensivos del Hospital Regional Docente de Trujillo en el periodo del 2015–2018. RESULTADOS: La mortalidad en el grupo con y sin hipernatremia fue de 38% y 6% respectivamente (p=0,001). La diferencia de medias de la natremia entre el grupo con y sin mortalidad fue de 21,86 (IC 95% 18,2-25,5) (p=0,000). En el análisis multivariado encontramos a la hipernatremia con OR ajustado de 16,73 (IC 95% 1,96-142,82) (p=0,01). La curva ROC mostró un rendimiento adecuado para predecir la mortalidad, con un AUC de 0,878 (IC 95% 0,77-0,97) (p=0,000). CONCLUSIÓN: La hipernatremia es un factor pronóstico de mortalidad en pacientes con trauma encefalocraneano severo.

INTRODUCTION: A severe traumatic brain injury is a frequent pathology, it implies a non-negligible morbidity and mortality. Hypernatremia could be considered a factor associated with poor prognosis in order to optimize treatment in the group of high-risk patients. OBJECTIVE: To determine if hypernatremia is a prognostic factor of mortality in patients with severe traumatic brain injury in a public hospital wich is a local reference center in trauma. MATERIAL AND METHOD: We performed a non-probabilistic sampling of adult patients of both sexes with severe traumatic brain injury from the Intensive Care Unit of the Hospital Regional Docente de Trujillo during the 2015–2018 period. RESULTS: Mortality in the group with and without hypernatremia was 38% and 6% respectively (p=0.001). The difference in natremia means values between the group with and without mortality was 21,86 (95% CI 18.2-25.5) (p=0.000). In the multivariate analysis, we found hypernatremia with adjusted OR of 16.73 (95% CI 1.96-142.82) (p=0.01). The ROC curve showed adequate performance to predict mortality, with an AUC 0.878 (95% CI 0.77-0.97) (p=0.00). CONCLUSION: Hypernatremia is a prognostic factor of mortality in patients with severe traumatic brain injury.

Tesis

Country
Peru
Keywords

Trauma encefalocraneano, Mortalidad, Hipernatremia

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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